Javier Corral Selected Research

Serpins

1/2016	Identification of Regulatory Mutations in SERPINC1 Affecting Vitamin D Response Elements Associated with Antithrombin Deficiency.
11/2012	Protective role of antithrombin in mouse models of liver injury.
9/2007	Factors with conformational effects on haemostatic serpins: implications in thrombosis.
4/2007	Protein Z/Z-dependent protease inhibitor (PZ/ZPI) anticoagulant system and thrombosis.
8/2006	Intracellular retention of hepatic serpins caused by severe hyperlipidemia.
7/2006	L-asparaginase-induced antithrombin type I deficiency: implications for conformational diseases.
2/2005	Thrombosis as a conformational disease.
9/2004	Homozygous deficiency of heparin cofactor II: relevance of P17 glutamate residue in serpins, relationship with conformational diseases, and role in thrombosis.
1/2004	What can Drosophila tell us about serpins, thrombosis and dementia?

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Javier Corral Research Topics

Disease

27	Thrombosis (Thrombus) 01/2022 - 08/2002
21	Venous Thrombosis (Deep-Vein Thrombosis) 11/2021 - 08/2002
13	Myocardial Infarction 09/2010 - 08/2002
11	Thrombophilia 01/2022 - 05/2008
9	Hemorrhage 10/2021 - 01/2003
8	Venous Thromboembolism 02/2021 - 05/2008
7	Inflammation (Inflammations) 01/2021 - 09/2004
6	Neoplasms (Cancer) 01/2021 - 01/2011
6	Cardiovascular Diseases (Cardiovascular Disease) 01/2013 - 07/2003
5	Atrial Fibrillation 10/2021 - 09/2004
5	Congenital, Hereditary, and Neonatal Diseases and Abnormalities (Congenital Disorders) 01/2020 - 10/2013
3	Congenital Disorders of Glycosylation 01/2022 - 11/2019
3	Ischemic Stroke 08/2012 - 09/2006
3	Stroke (Strokes) 08/2012 - 09/2006
2	Inborn Genetic Diseases (Disease, Hereditary) 08/2022 - 01/2018
2	Vascular Diseases (Vascular Disease) 01/2021 - 08/2012
2	COVID-19 01/2021 - 01/2021
2	Triple Negative Breast Neoplasms 12/2020 - 07/2019
2	Pulmonary Embolism 12/2019 - 06/2010
2	Protein S Deficiency (Deficiency, Protein S) 01/2017 - 04/2007
2	Neoplasm Metastasis (Metastasis) 01/2016 - 01/2016
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2014 - 07/2006
2	Necrosis 01/2013 - 02/2008
2	Cardiotoxicity 01/2013 - 02/2012
2	Atherosclerosis 08/2012 - 09/2004
2	Peripheral Arterial Disease 08/2012 - 08/2006
2	Sepsis (Septicemia) 01/2011 - 04/2005
2	Hyperlipidemias (Hyperlipidemia) 09/2007 - 08/2006
1	Disease Susceptibility (Diathesis) 01/2021
1	Angioedema 10/2020
1	Rare Diseases (Rare Disease) 10/2020
1	Hereditary Angioedemas 01/2020
1	Bacterial Infections (Bacterial Infection) 12/2019
1	Thromboembolism 12/2019
1	Plasmablastic Lymphoma 09/2019
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2019
1	Cerebellar Diseases (Cerebellar Syndrome) 01/2019
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Asthenia 01/2019

Drug/Important Bio-Agent (IBA)

40	AntithrombinsIBA 01/2022 - 11/2003
12	AnticoagulantsIBA 10/2021 - 04/2007
9	Hemostatics (Antihemorrhagics)IBA 10/2020 - 03/2005
9	SerpinsIBA 01/2016 - 01/2004
8	Proteins (Proteins, Gene)FDA Link 01/2020 - 08/2006
6	Factor XIII (Coagulation Factor XIII)IBA 09/2010 - 08/2002
5	Protein CIBA 12/2019 - 04/2007
4	Factor XII (Hageman Factor)IBA 10/2020 - 12/2005
3	phosphomannomutaseIBA 01/2022 - 01/2019
3	Glycoproteins (Glycoprotein)IBA 01/2022 - 07/2003
3	Heparin (Liquaemin)FDA LinkGeneric 01/2021 - 01/2016
3	Fibrinogen (Factor I)FDA Link 01/2021 - 09/2004
3	Thrombin FDA Link 01/2021 - 03/2009
3	Congenital disorder of glycosylation type 1AIBA 10/2020 - 10/2013
3	factor V LeidenIBA 11/2010 - 05/2008
3	Protease Inhibitors (Protease Inhibitor)IBA 04/2007 - 05/2005
3	plasma protein Z (protein Z)IBA 04/2007 - 05/2005
2	Factor XI (Plasma Thromboplastin Antecedent)IBA 10/2021 - 11/2019
2	Polysaccharides (Glycans)IBA 01/2020 - 01/2017
2	Blood Coagulation Factors (Coagulation Factor)IBA 11/2019 - 01/2017
2	Bortezomib (Velcade)FDA Link 09/2019 - 03/2008
2	Lenalidomide (CC 5013)FDA Link 09/2019 - 01/2018
2	MicroRNAs (MicroRNA)IBA 01/2017 - 03/2011
2	Thromboplastin (Tissue Factor)IBA 01/2016 - 09/2004
2	Factor VIII (Coagulation Factor VIII)IBA 09/2013 - 01/2013
2	AnthracyclinesIBA 01/2013 - 02/2012
2	LipidsIBA 08/2010 - 08/2006
2	antithrombin Cambridge IIIBA 03/2009 - 05/2007
2	Prothrombin (Factor II)IBA 05/2008 - 08/2002
2	N- (oxo- 5,6- dihydrophenanthridin- 2- yl)- N,N- dimethylacetamide hydrochlorideIBA 02/2008 - 04/2005
2	Integrin alpha2IBA 01/2008 - 07/2003
2	Asparaginase (Elspar)FDA Link 09/2007 - 07/2006
2	FibrinIBA 09/2006 - 04/2005
2	Annexin A5IBA 12/2002 - 09/2002
1	Retroelements (Retrotransposon)IBA 08/2022
1	von Willebrand FactorIBA 01/2021
1	fibrin fragment D (D-dimer)IBA 01/2021
1	Cyclooxygenase 1IBA 01/2021
1	Dacarbazine (DIC)FDA LinkGeneric 01/2021
1	Formaldehyde (Formol)FDA Link 01/2021
1	ParaffinIBA 01/2021
1	atezolizumabIBA 12/2020
1	130-nm albumin-bound paclitaxelIBA 12/2020
1	ElementsIBA 10/2020
1	Estrogens (Estrogen)FDA Link 01/2020
1	Oral ContraceptivesIBA 12/2019
1	Protein Isoforms (Isoforms)IBA 12/2019
1	Protein SIBA 12/2019
1	Acetazolamide (Diamox)FDA LinkGeneric 01/2019
1	Neuraminidase (Sialidase)IBA 01/2019
1	Bicarbonates (Hydrogen Carbonate)IBA 01/2019
1	Inosine Triphosphate (ITP)IBA 01/2019
1	voltage-dependent calcium channel (P-Q type)IBA 01/2019
1	N-Acetylneuraminic Acid (Sialic Acid)IBA 01/2019
1	Initiator Codon (Start Codon)IBA 09/2018
1	Indicators and Reagents (Reagents)IBA 01/2018

Therapy/Procedure

8	Therapeutics 10/2021 - 10/2005
4	Thrombolytic Therapy 09/2010 - 08/2002
2	Drug Therapy (Chemotherapy) 01/2021 - 12/2020
1	Immunotherapy 12/2020
1	Adjuvant Chemotherapy 07/2019